Twin pregnancy outcome following teriflunomide treatment in a relapsing-remitting multiple sclerosis patient

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Pregnancy Outcomes Following Maternal and Paternal Exposure to Teriflunomide During Treatment for Relapsing–Remitting Multiple Sclerosis

INTRODUCTION Teriflunomide, indicated for the treatment of relapsing-remitting multiple sclerosis, is contraindicated in pregnancy based on signs of developmental toxicity in the offspring of rats and rabbits; developmental toxicity has also been observed in preclinical studies of other disease-modifying therapies. Despite the requirement to use reliable contraception in clinical trials evaluat...

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ژورنال

عنوان ژورنال: Medicine

سال: 2020

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000021212